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From234US$ /night
Check-in
23Jan2026Select date
Check-out
24Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1528 Locust Street, Saint Louis, Missouri, United States, 63103
-
Steps from the Gateway Arch
Great
8.4
8.9
/10
4.2
4.1
/5

Rooms & Accommodations

21c Museum Hotel St Louis offers rooms ranging from Double Queen to 21c King Suite. Each room includes air conditioning, a seating area, a wardrobe, a safe deposit box, and a flat-screen TV with streaming services. Higher-tier suites feature kitchens, fireplaces, or fitness lofts. Bathrooms come with Malin+Goetz toiletries and either walk-in showers or soaking tubs.

Dining at Idol Wolf

Idol Wolf, the onsite restaurant, serves Spanish-inspired tapas with Midwestern ingredients. Dishes include Iberian classics reimagined with local produce. Breakfast options feature locally roasted coffee from Northwest Coffee and teas from Big Heart Tea Co.

Art & Fitness

The hotel houses rotating contemporary art exhibitions accessible 24/7. Locust Street Athletic Club includes a historic 4-lane lap pool, sauna, steam room, and fitness center open around the clock. Personal and group training sessions are available.

Downtown Location

Situated in Downtown St Louis, the hotel is a 5-minute walk from Busch Stadium and Citygarden Sculpture Park. The Gateway Arch is 2.5 km away. St Louis Lambert International Airport is a 20-minute drive.

Services & Events

21c offers guided art tours, laundry service, and in-room dining. Meeting spaces accommodate up to 280 guests with AV support. Wedding packages include catering by Idol Wolf. The hotel partners with local nonprofits like Power4STL.

“This property impressed me with its commitment to art and culture, creating a unique atmosphere that extends from the lobby to the guest rooms. I was particularly drawn to the innovative dining experiences and the holistic wellness options available, making it a standout destination. It seems like a perfect blend of artistic inspiration and luxurious comfort right in downtown Saint Louis.”
Hotel logo
Grace WhitmanContent & Editorial Director at Familyhotels
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Choose from a variety of room types

Choose from a wide variety of rooms designed for families, including double rooms, family suites, and rooms with breakfast included
Deluxe King Room
2 persons
315 sq. feet 
1 King-size bed
Shower
Heating
Deluxe King Suite Roll Shower Accessible
2 persons
510 sq. feet 
1 King-size bed
Shower
Heating
Loft Two Queen Beds
2 persons
435 sq. feet 
2 King Size Beds
Shower
Heating
Deluxe King Room Accessible
2 persons
315 sq. feet 
1 King-size bed
Shower
Heating
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Availability and pricing for your selected dates

Book your family’s getaway in a snap with up-to-date availability and pricing!

Facilities

Each family-friendly hotel provides top-notch amenities for an unforgettable stay with your loved ones

General

  • No smoking on site
  • Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Coffee shop
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Billiard tables
  • Yoga class

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities

Children

  • Cots
  • Board games
  • Game room

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Leisure/ TV room
  • Spa & wellness centre
  • Steam room
  • Jacuzzi
  • Massage

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • Direct dial telephone
  • AM/FM alarm clock
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Location

1528 Locust Street, Saint Louis, Missouri, United States, 63103
Map view
1528 Locust Street, Saint Louis, Missouri, United States, 63103
Nearby
Museum
City Museum
1800 ft
Museum
Campbell House Museum
300 ft
Church
Christ Church Cathedral
1500 ft
1315 Chestnut St
Soldiers Memorial Military Museum
2000 ft
Aquarium
World Aquarium
1400 ft
Church
Centenary United Methodist Church
700 ft
Night club
The Boom Boom Room
1000 ft
13th and Locust
Lucas Garden Park
1200 ft
Restaurants
The Last Kitchen
1200 ft
1501 Washington Ave Inside The Last Hotel
Red Oak Biscuits
1100 ft
1330 Washington Ave
Nara Cafe and Hookah Lounge
1100 ft
1326 Washington Ave
Flannery's
1300 ft
1324 Washington Ave
Rooftop Cafe at City Museum
1400 ft
701 N 15th St Fl 11
Lucas Park Grille
1500 ft
1234 Washington Avenue
Rosalita's Cantina
1600 ft
1235 Washington Avenue
Blondie's Coffee
1500 ft
1301 Washington Ave
Imo's Pizza
1400 ft
1828 Washington Ave
Papa John's Pizza
2100 ft
201 N Tucker Blvd Ste E
Bootleggin' BBQ
2200 ft
1933 Washington Ave
Explore Saint Louis
Explore St. Louis
Top Attractions
Activities
Dining
Entertainment
City Museum
City Museum
5 minutes walking
A quirky blend of playground and art space, the City Museum features slides, tunnels, and stunning artwork throughout.
Campbell House Museum
Campbell House Museum
2 minutes walking
An elegant 19th-century mansion showcasing period furnishings, the Campbell House offers guided tours for history enthusiasts.
The Gateway Arch
The Gateway Arch
25 minutes walking
Iconic symbol of St. Louis, the Gateway Arch stands 630 feet tall. Visitors enjoy stunning views from its observation deck.
National Blues Museum
National Blues Museum
16 minutes walking
Celebrating the history of blues music, this museum features interactive exhibits and performances for music fans.
St. Louis Riverfront
5 minutes driving
A scenic area for jogging or biking with river views and lush green spaces. Enjoy trails and historical sites nearby.
Yoga at Forest Park
10 minutes driving
Relaxing outdoor yoga sessions held at beautiful Forest Park, ideal for rejuvenation amid nature. Classes available seasonally.
The Last Kitchen
The Last Kitchen
5 minutes walking
Serving American cuisine with a twist, The Last Kitchen offers a cozy atmosphere and signature dishes like fried chicken.
Red Oak Biscuits
Red Oak Biscuits
4 minutes walking
Known for its delicious breakfast biscuits, this casual spot features a warm atmosphere and fresh, farm-to-table ingredients.
Rooftop Cafe at City Museum
Rooftop Cafe at City Museum
5 minutes walking
Casual dining with fantastic views of the city. Enjoy unique sandwiches and craft beers while overlooking the skyline.
Stifel Theatre
Stifel Theatre
8 minutes walking
An elegant venue for concerts and performances. Enjoy a varied lineup, from classical music to contemporary acts.
National Blues Museum
National Blues Museum
16 minutes walking
Catch live blues performances and immerse yourself in interactive exhibits celebrating the rich heritage of blues music.
Tips on navigating the city
City Centre
Saint Louis8 min  ·  2000 ft
Airports
St. Louis Lambert International Airport (STL)33 min  ·  13.5 mi
Belleville, IL (BLV)62 min  ·  25.4 mi
Train
Union Station9 min  ·  2300 ft
Bus
Bus stop3 min  ·  700 ft
Get access to exclusive early booking discounts for your family’s upcoming getaway
Book now and enjoy exclusive rates on your family vacation!
Check Rates
Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in for free.
Pets
Pets are allowed on request.
Number of floors:
10
Number of rooms:
137
FAQs
About 21C Museum Hotel St Louis
What is the check-in and check-out policy at 21C Museum Hotel St Louis?
Check-in is from 16:00 and check-out is by 11:00.
How far is 21C Museum Hotel St Louis from St Louis Lambert International Airport?
The hotel is approximately 21 km from St Louis Lambert International Airport.
What recreational facilities are available at 21C Museum Hotel St Louis?
Guests have access to an indoor swimming pool, hot tub, fitness center, and spa services.
Which notable attractions are located near 21C Museum Hotel St Louis?
Nearby attractions include the Gateway Arch (3 km), Edward Jones Dome (2 km), and Old Courthouse (2 km).
What dining options are available at 21C Museum Hotel St Louis?
The hotel features an on-site restaurant that serves Spanish cuisine and a lounge bar.
What amenities are included in the guest rooms at 21C Museum Hotel St Louis?
Rooms include air conditioning, a flat-screen TV with cable channels, a safe deposit box, and a private bathroom with free toiletries.
Is parking available at 21C Museum Hotel St Louis?
Valet parking is available on-site for guests.
What wellness options can guests find at 21C Museum Hotel St Louis?
The hotel offers a spa and wellness center, yoga classes, steam room, and massage services.
How far is 21C Museum Hotel St Louis from popular dining venues?
Popular nearby restaurants, such as Samwiches, Rooftop Cafe at City Museum, and Red Oak Biscuits, are all within 0.5 km.
What business facilities does 21C Museum Hotel St Louis provide?
The hotel features a meeting room equipped with AV technology and a business center.
Does 21C Museum Hotel St Louis offer free Wi-Fi?
Complimentary Wi-Fi is available throughout the property.
Are there leisure activities available at 21C Museum Hotel St Louis?
Guests can enjoy games such as billiards and explore temporary art galleries within the hotel.

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