21C Museum Hotel St Louis – Family Hotel in Saint Louis | From 350$/Night

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About the Hotel

1528 Locust Street, Saint Louis, Missouri, United States, 63103

“"The hotel's location offered vibrant surroundings and artistic flair."”view full review

Rooms & Accommodations

21c Museum Hotel St Louis offers rooms ranging from Double Queen to 21c King Suite. Each room includes air conditioning, a seating area, a wardrobe, a safe deposit box, and a flat-screen TV with streaming services. Higher-tier suites feature kitchens, fireplaces, or fitness lofts. Bathrooms come with Malin+Goetz toiletries and either walk-in showers or soaking tubs.

Dining at Idol Wolf

Idol Wolf, the onsite restaurant, serves Spanish-inspired tapas with Midwestern ingredients. Dishes include Iberian classics reimagined with local produce. Breakfast options feature locally roasted coffee from Northwest Coffee and teas from Big Heart Tea Co.

Art & Fitness

The hotel houses rotating contemporary art exhibitions accessible 24/7. Locust Street Athletic Club includes a historic 4-lane lap pool, sauna, steam room, and fitness center open around the clock. Personal and group training sessions are available.

Downtown Location

Situated in Downtown St Louis, the hotel is a 5-minute walk from Busch Stadium and Citygarden Sculpture Park. The Gateway Arch is 2.5 km away. St Louis Lambert International Airport is a 20-minute drive.

Services & Events

21c offers guided art tours, laundry service, and in-room dining. Meeting spaces accommodate up to 280 guests with AV support. Wedding packages include catering by Idol Wolf. The hotel partners with local nonprofits like Power4STL.

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Choose from a variety of room types

Choose from a wide variety of rooms designed for families, including double rooms, family suites, and rooms with breakfast included

Corner King Room

2 persons

30 m²

1 King-size bed

Shower

Heating

room details

Deluxe King Room

2 persons

29 m²

1 King-size bed

Shower

Heating

room details

Corner King Suite

2 persons

44 m²

1 King-size bed

Shower

Heating

room details

Deluxe King Suite Roll Shower Accessible

2 persons

47 m²

1 King-size bed

Shower

Heating

room details

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Availability and pricing for your selected dates

Book your family’s getaway in a snap with up-to-date availability and pricing!

Tips on navigating the city

Access a full list of transport options to make getting around with your family easy

City Centre

Saint Louis600 m

Airports

Lambert (STL) 21.8 km

MidAmerica St. Louis/Scott Air Force Base (BLV) 40.8 km

Train

Union Station700 m

Bus

Bus stop200 m

Facilities

Each family-friendly hotel provides top-notch amenities for an unforgettable stay with your loved ones

Really good Culinary Experience

“I dined at Idol Wolf and it was fantastic! The food was not only delicious but beautifully presented. From breakfast to dinner, each meal was a delight. The Eggs Benedict were especially excellent, making it a highlight of my stay.” view full review

Wellness Retreat

“The wellness facilities blew me away! The pool was large, slightly warm, and well-kept. I enjoyed the hot tub that was roomy and inviting. Plus, the sauna and steam room provided a perfect way to unwind after a long day.” view full review

Comfortable and Stylish Rooms

“The room I stayed in was beautiful and well-appointed. I loved the temperature control in the bathroom, as it made my morning routine so much more comfortable. The design of the space was both modern and inviting, a true haven.” view full review

Artistic Immersion

“The art gallery on the second floor was a highlight of my stay. Each piece was thoughtfully curated, and I found myself captivated by the unique installations. It was a good experience that added a special touch to my visit.” view full review

General

No smoking on site
Free Wi-Fi
Safe deposit box
24-hour reception
VIP check-in/ -out
Pets allowed
Rooms/ Facilities for disabled
Wheelchair access
24-hour security
Luggage storage
Locker room
Allergy-free rooms
Lift
ATM/Cash machine
Coffee shop
Vending machines
Smoke detectors
Fire extinguishers
Key card access

Sports & Fitness

Fitness centre
Billiard tables
Yoga class

Services

Valet parking
Room service
Housekeeping
Laundry
Dry cleaning
Welcome drink

Dining

Restaurant
Bar/ Lounge area
Special diet menus

Business

Business centre
Meeting/ Banquet facilities

Children

Cots
Board games
Game room

Facilities for people with disabilities

Toilet for disabled

Spa & Leisure

Indoor swimming pool
Leisure/ TV room
Spa & wellness centre
Steam room
Jacuzzi
Massage

Room features

Air conditioning
Heating
Soundproofed rooms
Sitting area
Terrace
Garden furniture

Bathroom

Free toiletries

Media

Flat-screen TV

Location

1528 Locust Street, Saint Louis, Missouri, United States, 63103

Map view

1528 Locust Street, Saint Louis, Missouri, United States, 63103

City landmarks

Stadium

Busch Stadium

1.6 km

Museum

The Gateway Arch

1.9 km

Opera House

Stifel Theatre

660 m

Landmark

Old Courthouse

1.6 km

Landmark

Scott Joplin House State Historic Site

1.2 km

Stadium

Edward Jones Dome

1.4 km

Event hall

America's Center

1.4 km

Landmark

Cardinals Hall of Fame and Museum

1.6 km

Landmark

Security Building

1.3 km

Hockey Stadium

Savvis Center

850 m

Landmark

Citygarden Sculpture Park

1.2 km

Museum

National Blues Museum

1.2 km

Landmark

Kiener Plaza

620 m

Landmark

Inside the Economy Museum at the Federal Reserve Bank

1.3 km

Landmark

The Old Post Office and Custom House

910 m

Landmark

Museum of Westward Expansion

1.4 km

Fountain

Milles Fountain

620 m

Public Building

St. Louis City Hall

630 m

Landmark

Wainwright Building

1.0 km

Church

Shrine of St Joseph

1.1 km

Landmark

The Hill

820 m

Library

Central Public Library

830 m

Nearby

Museum

City Museum

520 m

Museum

Campbell House Museum

90 m

Church

Christ Church Cathedral

430 m

1315 Chestnut St

Soldiers Memorial Military Museum

590 m

Aquarium

World Aquarium

400 m

Church

Centenary United Methodist Church

190 m

Night club

The Boom Boom Room

280 m

13th and Locust

Lucas Garden Park

350 m

Restaurants

The Last Kitchen

360 m

1501 Washington Ave Inside The Last Hotel

Red Oak Biscuits

310 m

1330 Washington Ave

Nara Cafe and Hookah Lounge

310 m

1326 Washington Ave

Flannery's

380 m

1324 Washington Ave

Rooftop Cafe at City Museum

400 m

701 N 15th St Fl 11

Lucas Park Grille

440 m

1234 Washington Avenue

Rosalita's Cantina

480 m

1235 Washington Avenue

Blondie's Coffee

450 m

1301 Washington Ave

Imo's Pizza

410 m

1828 Washington Ave

Papa John's Pizza

610 m

201 N Tucker Blvd Ste E

Bootleggin' BBQ

650 m

1933 Washington Ave

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21C Museum Hotel St Louis – A Favorite for Families in Saint Louis

About the Hotel

Rooms & Accommodations

Dining at Idol Wolf

Art & Fitness

Downtown Location

Services & Events

Choose from a variety of room types

Availability and pricing for your selected dates

Tips on navigating the city

Facilities

General

Sports & Fitness

Services

Dining

Business

Children

Facilities for people with disabilities

Spa & Leisure

Room features

Bathroom

Media

Location

Next best alternative