21C Museum Hotel St Louis Saint Louis Exterior photo21C Museum Hotel St Louis Saint Louis Exterior photo21C Museum Hotel St Louis Saint Louis Exterior photo

21C Museum Hotel St Louis – A Favorite for Families in Saint Louis

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Check rooms and rates
From$234 /night
Check-in
17Jun
Check-out
18Jun
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1528 Locust Street, Saint Louis, 63103
-
Steps from the Gateway Arch
Great
8.5
8.8
/10
4.2
4.2
/5

Rooms & Accommodations

21c Museum Hotel St Louis offers rooms ranging from Double Queen to 21c King Suite. Each room includes air conditioning, a seating area, a wardrobe, a safe deposit box, and a flat-screen TV with streaming services. Higher-tier suites feature kitchens, fireplaces, or fitness lofts. Bathrooms come with Malin+Goetz toiletries and either walk-in showers or soaking tubs.

Dining at Idol Wolf

Idol Wolf, the onsite restaurant, serves Spanish-inspired tapas with Midwestern ingredients. Dishes include Iberian classics reimagined with local produce. Breakfast options feature locally roasted coffee from Northwest Coffee and teas from Big Heart Tea Co.

Art & Fitness

The hotel houses rotating contemporary art exhibitions accessible 24/7. Locust Street Athletic Club includes a historic 4-lane lap pool, sauna, steam room, and fitness center open around the clock. Personal and group training sessions are available.

Downtown Location

Situated in Downtown St Louis, the hotel is a 5-minute walk from Busch Stadium and Citygarden Sculpture Park. The Gateway Arch is 2.5 km away. St Louis Lambert International Airport is a 20-minute drive.

Services & Events

21c offers guided art tours, laundry service, and in-room dining. Meeting spaces accommodate up to 280 guests with AV support. Wedding packages include catering by Idol Wolf. The hotel partners with local nonprofits like Power4STL.

“This property impressed me with its commitment to art and culture, creating a unique atmosphere that extends from the lobby to the guest rooms. I was particularly drawn to the innovative dining experiences and the holistic wellness options available, making it a standout destination. It seems like a perfect blend of artistic inspiration and luxurious comfort right in downtown Saint Louis.”
Hotel logo
Grace WhitmanContent & Editorial Director at Familyhotels

Choose from a variety of room types

Choose from a wide variety of rooms designed for families, including double rooms, family suites, and rooms with breakfast included
  • Deluxe King Room
    2 persons
    29 sq. feet
    1 King-size bed
    Air conditioning
    Heating
  • Deluxe King Suite Roll Shower Accessible
    2 persons
    47 sq. feet
    1 King-size bed
    Air conditioning
    Heating
  • Loft Two Queen Beds
    2 persons
    40 sq. feet
    2 King Size Beds
    Air conditioning
    Bathtub
Show all rooms

Availability and pricing for your selected dates

Book your family’s getaway in a snap with up-to-date availability and pricing!
June 2026 - June 2027
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June 2026
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Choose dates to see prices
Check-in/ Check-out

Facilities

Each family-friendly hotel provides top-notch amenities for an unforgettable stay with your loved ones
Facilities: Great
8.7/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Coffee shop
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Billiard tables
  • Yoga class

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities

Children

  • Cots
  • Board games
  • Game room

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Leisure/ TV room
  • Spa & wellness centre
  • Steam room
  • Jacuzzi
  • Massage

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • Direct dial telephone
  • AM/FM alarm clock
Show more

21C Museum Hotel St Louis Location

1528 Locust Street, Saint Louis, 63103
Explore Saint Louis
Explore St. Louis
  • Top Attractions
  • Activities
  • Dining
  • Entertainment
City Museum
City Museum
5 minutes walking
A quirky blend of playground and art space, the City Museum features slides, tunnels, and stunning artwork throughout.
Campbell House Museum
Campbell House Museum
2 minutes walking
An elegant 19th-century mansion showcasing period furnishings, the Campbell House offers guided tours for history enthusiasts.
The Gateway Arch
The Gateway Arch
25 minutes walking
Iconic symbol of St. Louis, the Gateway Arch stands 630 feet tall. Visitors enjoy stunning views from its observation deck.
National Blues Museum
National Blues Museum
16 minutes walking
Celebrating the history of blues music, this museum features interactive exhibits and performances for music fans.
St. Louis Riverfront
5 minutes driving
A scenic area for jogging or biking with river views and lush green spaces. Enjoy trails and historical sites nearby.
Yoga at Forest Park
10 minutes driving
Relaxing outdoor yoga sessions held at beautiful Forest Park, ideal for rejuvenation amid nature. Classes available seasonally.
The Last Kitchen
5 minutes walking
Serving American cuisine with a twist, The Last Kitchen offers a cozy atmosphere and signature dishes like fried chicken.
Red Oak Biscuits
4 minutes walking
Known for its delicious breakfast biscuits, this casual spot features a warm atmosphere and fresh, farm-to-table ingredients.
Rooftop Cafe at City Museum
5 minutes walking
Casual dining with fantastic views of the city. Enjoy unique sandwiches and craft beers while overlooking the skyline.
Stifel Theatre
Stifel Theatre
8 minutes walking
An elegant venue for concerts and performances. Enjoy a varied lineup, from classical music to contemporary acts.
National Blues Museum
National Blues Museum
16 minutes walking
Catch live blues performances and immerse yourself in interactive exhibits celebrating the rich heritage of blues music.
Tips on navigating the city
  • City Centre
    Saint Louis 8 min  ·  2000 ft
  • Airports
    Lambert (STL) 33 min  ·  13.5 mi
    MidAmerica St. Louis/Scott Air Force Base (BLV) 62 min  ·  25.4 mi
  • Train
    Union Station 9 min  ·  2300 ft
  • Bus
    Bus stop 3 min  ·  700 ft
Get access to exclusive early booking discounts for your family’s upcoming getaway
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Check Rates
Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
Wireless internet is available in the entire hotel for free.
Pets
Pets are allowed on request.
Number of floors:
10
Number of rooms:
137

Family-focused reviews and ratings

Read feedback from other families who have stayed to ensure you make the right choice.
Review score
Based on 1621 verified reviews
8.3 /10
Great
78 %
Recommend
Breakfast
6.6/10
Cleanliness
8.8/10
Comfort
8.7/10
Facilities
8.7/10
Free WiFi
7.9/10
Location
8.6/10
Paid Wi-Fi
5.9/10
Staff
8.7/10
Value for money
8.0/10
Pros
Amazing museum
Fantastic customer service
Nice pool
Well-curated museum
Cons
Rude valet
Small room
Early spa closure
Elevator issues
Guest reviews
based on 1046 reviews
8.5/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews
FAQs
About 21C Museum Hotel St Louis
What is the check-in and check-out policy at 21C Museum Hotel St Louis?
Check-in is from 16:00 and check-out is by 11:00.
How far is 21C Museum Hotel St Louis from St Louis Lambert International Airport?
The hotel is approximately 21 km from St Louis Lambert International Airport.
What recreational facilities are available at 21C Museum Hotel St Louis?
Guests have access to an indoor swimming pool, hot tub, fitness center, and spa services.
Which notable attractions are located near 21C Museum Hotel St Louis?
Nearby attractions include the Gateway Arch (3 km), Edward Jones Dome (2 km), and Old Courthouse (2 km).
What dining options are available at 21C Museum Hotel St Louis?
The hotel features an on-site restaurant that serves Spanish cuisine and a lounge bar.
What amenities are included in the guest rooms at 21C Museum Hotel St Louis?
Rooms include air conditioning, a flat-screen TV with cable channels, a safe deposit box, and a private bathroom with free toiletries.
Is parking available at 21C Museum Hotel St Louis?
Valet parking is available on-site for guests.
What wellness options can guests find at 21C Museum Hotel St Louis?
The hotel offers a spa and wellness center, yoga classes, steam room, and massage services.
How far is 21C Museum Hotel St Louis from popular dining venues?
Popular nearby restaurants, such as Samwiches, Rooftop Cafe at City Museum, and Red Oak Biscuits, are all within 0.5 km.
What business facilities does 21C Museum Hotel St Louis provide?
The hotel features a meeting room equipped with AV technology and a business center.
Does 21C Museum Hotel St Louis offer free Wi-Fi?
Complimentary Wi-Fi is available throughout the property.
Are there leisure activities available at 21C Museum Hotel St Louis?
Guests can enjoy games such as billiards and explore temporary art galleries within the hotel.

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17Jun
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